Osh - Tashkent

The journey begins in Osh, heading east through the suburb of Dostlik, a mostly residential area at the edge of the city. After the border, travelers meet their new guide and driver, ensuring a smooth continuation into Uzbekistan.

The road then opens onto the fertile Ferghana Valley, one of Central Asia’s richest agricultural regions, stretching over 7,000 km² across Uzbekistan, Kyrgyzstan, and Tajikistan. Between Andijan and the Kalmik Pass, the landscape is dotted with orchards, melon and cotton fields, and villages where traditional crafts, lively bazaars, and Uzbek tea houses reflect centuries of local culture. Travelers may glimpse historic caravan towns, vibrant markets, and the everyday rhythm of life in this historic Silk Road region.

The route finally climbs gently over the Kalmik Pass, offering sweeping views over the valley before descending toward Tashkent, Uzbekistan’s capital. 

While the journey can be done in one long day, we recommend splitting it into two days to fully enjoy the rich cultural and historical stops of the Ferghana Valley — a choice that also supports a more sustainable, lower-emission approach to travel.